Dry Eye Curly Coat Syndrome in the Cavalier King Charles Spaniel
Dry eye and curly coat syndrome appears to be a problem unique to Cavalier King Charles Spaniels and most dogs diagnosed with the condition are put to sleep. Known scientifically as congenital keratoconjunctivitis sicca and ichtyosiform dermatosis, dry eye and curly coat syndrome affects a dog’s eyes and skin. Affected dogs produce no tears making their eyes incredibly sore. Their skin becomes very flaky and dry, particularly around the foot, and this can make standing and walking difficult and painful.
Early in 2011 Geneticists at the Animal Health Trust identified a recessive mutation associated with Dry Eye Curly Coat Syndrome. A DNA test was developed to provide a useful diagnostic tool to the veterinary profession and dog breeders and has been available from the Animal Health Trust since 18 April 2011. The DNA test is specific to the mutation causing Dry Eye and Curly Coat Syndrome.
Breeders using the test will be sent results identifying their dog as belonging to one of three categories:
CLEAR: these dogs have two normal copies of DNA. Clear dogs will not be affected by Dry Eye Curly Coat Syndrome as a result of the associated mutation identified.
CARRIER: these dogs have one copy of the mutation and one normal copy of DNA. These dogs will not develop Dry Eye Curly Coat Syndrome themselves but they will pass the mutation on to approximately 50% of their offspring.
AFFECTED: these dogs have two copies of the mutation associated with Dry Eye Curly Coat Syndrome and will be clinically affected.
Please note that is it is possible for some Cavaliers to be affected by non congenital forms of ichthyosis or dry eye which will not be detected by the DNA test.
Tests should be ordered from our online webshop
Enquiries should be made to Symone Ingram telephone +44 (0) 1638 555621 or fax +44 (0) 1638 555666 or via e-mail to firstname.lastname@example.org.
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