HELP OUR RESEARCH INTO CANINE CANCER
At the AHT, clinicians and scientists work together on research aiming to help both dogs with cancer and vets treating dogs with cancer. However, we need your help to collect the samples required for the research to progress. We have two main areas of research:
Development of prognostic tests
For several canine cancers (e.g. mast cell tumours), we are attempting to develop objective and quantitative tests that predict how individual tumours will behave and respond to treatment. The availability of such tests would assist vets to make more informed decisions about the most appropriate treatment for a dog with cancer. This would ensure that dogs that require an adjunctive (and possibly aggressive) therapy receive that therapy, whilst dogs that wouldn’t benefit from such a therapy are spared the rigours and possible side effects associated with the therapy. For this research, we need to collect biopsies of suspected tumours (in ‘RNAlater’, a preservative that we provide) from dogs of any breed.
Identification of genetic risk factors
We are seeking to identify the inherited gene mutations that cause a number of pedigree dog breeds to have an increased risk of developing a specific cancer (e.g. osteosarcoma). In the long term, we hope that the research will lead to the development of DNA tests to identify dogs that carry the gene mutations conferring an increased risk. This information will be useful to vets as it will identify dogs who may benefit from careful monitoring for early detection of cancer, and thereby early treatment. These tests will also assist breeders to reduce the incidence of dogs affected with these cancers. The research will also increase understanding of how these tumours develop, ultimately assisting the development of new therapies. For this research, we need to collect cheeks swabs/surplus EDTA blood samples AND ideally also biopsies (in RNAlater) of suspected tumours from dogs belonging to particular breeds.
If you are interested in contributing to our cancer research effort by assisting us to collect samples, please contact us by e-mail to firstname.lastname@example.org or by telephoning 01638 751000 ext. 1214.