Recent increased presentation of acquired Fanconi-like syndrome cases related to dried chicken and duck meat ingestion in the UK.
A recent cluster of canine cases with PU/PD, glucosuria +/- ketonuria and without hyperglycaemia have been reported by number of referral practices and general practioners in the UK. This combination of findings is suggestive of a proximal tubular disorder and may also be associated with marked electrolyte and acid-base abnormalities. Where a dietary history has been available, the majority of these patients have been fed dried ‘jerky’ type dog treats (chicken and duck), of which many have been identified as originating from China.
Acquired proximal tubular disease has previously been reported in Australia and the USA, as well as small numbers of cases in the UK and Europe in association with the ingestion of dried jerky treats. As yet, specific toxins have not been identified within these treats as a cause.
Based upon previously published information, many pets presenting with these signs are responsive to discontinuation of treats alone when identified early in disease. However some patients with more significant acid-base and electrolyte disorders will require supportive medical therapy. A small percentage of cases are reported to die or are euthanased.
Assessment of dietary history is key to identifying potential cases and where a compatible presentation is identified, should be considered in addition to testing for other causes of acquired proximal tubular disease. Based upon information available from other countries, some dogs may also present with PU/PD and hypophosphataemia alone, without glucosuria.
We would urge veterinary surgeons throughout the UK to be aware of this potential presentation.
Posted: 3 February 2016
Thompson et al. Acquired proximal renal tubulopathy in dogs exposed to a common dried chicken treat: retrospective study of 108 cases (2007–2009). Australian Veterinary Journal. (2013), Vol 91: 368
USA Food and Drug Administration - http://www.fda.gov/animalveterinary/safetyhealth/productsafetyinformation/ucm360951.htm