give a dog a genome
Welcome to Give a Dog a Genome, a new initiative launched by the Kennel Club Genetics Centre at the AHT to create the UK’s largest canine genome bank to help generations of dogs.
This genome bank will improve dog health by radically increasing our understanding of the canine genome by sequencing the entire genome (all 2.4 billion letters of DNA) of a large number of different breeds.
Since Give a Dog a Genome (GDG) was launched in January, support for the project from breed communities has been extraordinary.
75 breeds have now registered their interest for the original 50 places on the project. We are therefore very pleased to say that in order to meet the enthusiasm of so many breeds we have been granted additional funding from the Kennel Club Charitable Trust of £25,000 to match-fund the sequencing of 75 genomes in total, one from 75 different breeds. This will create an even larger and more powerful canine genome bank to aid all of our future genetics research investigations. We would like to thank all breeds who have supported this project so far.
Click here to see the 75 breeds that will have a dog's genome sequenced and included in the canine genome bank.
As we start the exciting process of selecting dogs for sequencing, any additional breeds wishing to participate in Give a Dog a Genome will be entered into the second phase of the project, GDG2, that is expected to begin during 2017. Breeds that are entered into GDG2 will not be asked to make their £1,000 donation until 2017.
We will now begin a dialogue with each Breed regarding the choice of dog for sequencing. We will begin by asking breed health co-ordinators to provide information about their breed’s main health concerns. This will enable us to collate information from all the participating breeds and to decide if it will be more valuable to sequence a dog that is either affected with an inherited disorder of concern to the breed or an older, healthy dog, on a breed by breed basis. The final choice of dogs whose genomes are sequenced will be made by the Animal Health Trust and the identity of all dogs will be kept confidential.
What is Give a Dog a Genome?
Every genome we sequence is a permanent resource which will contribute towards our research for many years to come, to the benefit of all breeds – not just those we can sequence now.
By undertaking this colossal task - DNA is a string of A, C, G & Ts…if each was 1mm long the whole genome of each dog we sequence would stretch from Lands End to John O’Groats and back again! - we will enhance our understanding of which changes in DNA sequence have an effect on dog health and which changes are benign or neutral.
This information will have profound effects on our ability to identify mutations which cause inherited diseases in purebred dogs, and the rate at which we can develop new DNA tests as tools for breeders. Give a Dog a Genome will revolutionise canine genetics research and is therefore a hugely important project to the future of dog health.
BREEDS BACKING GIVE A DOG A GENOME
WHAT IS WHOLE GENOME SEQUENCING?
HOW YOU CAN SUPPORT GIVE A DOG A GENOME
GIVE A DOG A GENOME - FAQs
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