Genetics Tests

PLL TESTING -IMPORTANT

Please ensure that all samples returned for DNA testing for PLL are taken using an AHT diagnostic sampling kit (obtainable free of charge from swabrequest@aht.org.uk, please quote number of kits needed and the test required) OR 2mls EDTA blood. The only form we can accept for DNA Testing is headed "REQUEST FOR DNA TESTING". If you send in samples accompanied by forms headed "SAMPLE SUBMISSION FOR CANINE GENETIC RESEARCH" or "REQUEST FOR PRIMARY LENS LUXATION DNA RESEARCH RESULT" they cannot be processed and this can lead to long delays in dealing with your request.

The Animal Health Trust is a leading supplier of genetic testing to the veterinary profession and to breeders of dogs, horses, cattle and cats. The basic research for many of the DNA tests now available at the Animal Health Trust was carried out in our own research laboratories (see Genetics Research); in addition, we also offer DNA tests developed in genetics laboratories from around the world. Our range includes tests for hereditary disorders in dogs and cats, as well as traits such as yellow coat colour in Labrador Retrievers and chestnut coat colour in horses.

We also offer comprehensive DNA profiling and parentage testing services for dogs, horses and cattle.

A DNA test to determine a dog’s genotype with respect to Primary Lens Luxation (PLL) is now available. Testing kits can be requested by e-mail from swabrequest@aht.org.uk. If you do not have access to email please telephone 01638 555621 or fax 01638 555666.

Owners who submitted samples for the PLL research prior to September 1, 2009 may request test results using a form that will become available on this website on October 19th, 2009. Click on link for form http://www.aht.org.uk/pdf/pllresult.pdf

If you don't see a DNA test for the disease that you are interested in here, please contact us. We are constantly reviewing the range of DNA tests for hereditary diseases which we have on offer. We will consider introducing any test where we can identify a clear need in the UK population of pedigree dogs.

We are currently looking into the feasibility of offering tests for pyruvate kinase deficiency in Basenjis and ceroid lipofuscinosis in English Setters. The mutations for both these diseases are now known, but we need to identify carrier and affected dogs in order to validate the test in our laboratory. If anyone has such dogs and would be prepared to send in cheek swab samples (easily taken from the inside lining of the cheek and non-invasive), they would be making an invaluable contribution to developing DNA testing for these diseases in their breed in the UK. If you think you may be able to help us, please contact us at dnatesting@aht.org.uk or telephone +44 (0) 1638 555621 or fax +44 (0) 1638 555643. Any samples that you send will be handled in strictest confidence.

As a non-profit making organisation, our tests are priced competitively to cover costs - any surplus is re-invested in our research programme into animal disease and welfare.

Canine

For more information on available tests and prices please click on the links below

Test	Breed	Sample Required	Price (inc vat)	Request Form
Canine DNA Profiling	All breeds	Mouth Swabs	£34	pdf
Canine DNA Profiling ISAG2006	All breeds	Mouth Swabs	£34	pdf
Canine Parentage Testing	All breeds	Mouth Swabs	£24 per animal	pdf
Centronuclear Myopathy	Labrador Retrievers	Mouth Swabs	£42	pdf
Ceroid Lipofuscinosis	Border Collies	2mls EDTA blood ****	£42	pdf
Canine Leukocyte Adhesion Deficiency	Irish Setters Red & White Setters	2mls EDTA blood ****	£70	pdf
Cerebellar Ataxia	Spinone	Mouth Swabs	£60	pdf
Coagulation Factor VII Deficiency	Scottish Deerhound Beagle	Mouth Swabs	£70	pdf
Coat Length	Weimeraners Border Collies Pembroke Welsh Corgis German Shepherds Miniature Smooth Haired Dachshunds Alaskan Malamute	Mouth Swabs	£34	pdf
Congenital Stationary Night Blindness	Briards	Mouth Swabs	£56	pdf
Copper Toxicosis	Bedlington Terriers	Mouth Swabs	£56	pdf
Fucosidosis	English Springer Spaniels	Mouth Swabs	£48**	pdf
Fucosidosis *FOR SPRINGERKLUBBEN (SWEDEN) ONLY	English Springer Spaniels	Mouth Swabs	£48**	pdf
Hereditary Cataract	Australian Shepherd	Mouth Swabs	£67	pdf
Hereditary Cataract	French Bulldog	Mouth Swabs	£70	pdf
Hereditary Cataract	Staffordshire Bull Terrier	Mouth Swabs / 3mls EDTA blood ****	£70*	pdf
Early Onset Hereditary Cataracts	Boston Terrier	Mouth Swabs	£70	pdf
L-2-hydroxyglutaric aciduria	Staffordshire Bull Terrier	Mouth Swabs / 3mls EDTA blood ****	£67*	pdf
Primary Lens Luxation (PLL)	Chinese Crested Dog Jack Russell Terrier Jagd Terrier Lancashire Heeler Miniature Bull Terrier Parson Russell Terrier Patterdale Terrier Rat Terrier Sealyham Terrier Tenterfield Terrier Tibetan Terrier Volpino Italiano	Mouth Swabs OR 2mls EDTA blood **** (blood accepted only for dogs within European Union countries)	£40	pdf FAQs regarding the PLL DNA Test Clinical aspects of PLL DNA testing for breeders and owners
Phosphofructokinase Deficiency	English Springer Spaniels	2mls EDTA blood ****	£70	pdf
Progressive Retinal Atrophy (cord1)	English Springer Spaniels	Mouth Swabs	£47**	pdf
Progressive Retinal Atrophy (cord 1) *FOR SPRINGERKLUBBEN (SWEDEN) ONLY	English Springer Spaniels	Mouth Swabs	£47**	pdf
Progressive Retinal Atrophy (rcd1)	Irish Setters Red & White Setters	3-5mls EDTA blood ****	£70	pdf
Progressive Retinal Atrophy	Sloughis	2mls EDTA blood ****	£70	pdf
Progressive Retinal Atrophy	Miniature Long-Haired Miniature Smooth- Haired Miniature Wire-Haired Dachshunds	Mouth Swabs	£47	pdf
Pyruvate Dehydrogenase Phosphate 1 Deficiency (PDP1)	Sussex Spaniels Clumber Spaniels	Mouth Swabs	£70	pdf
Short -Tail (Bob-Tail) Gene	Australian Shepherds Boxer Pembroke Welsh Corgis	Mouth Swabs	£70	pdf
Urate Stones – Uric Acid Excretion (Canine Hyperuricosauria)	Russian Black Terriers Bulldogs Dalmatians Large Munsterlanders	Mouth Swabs	£70	pdf
Von Willebrands Disease	Irish Red & White Setters	Mouth Swabs	£70	pdf
Yellow Coat Gene	Labrador Retrievers Flat Coated Retrievers	2mls EDTA blood ****	£70	pdf
Feline
Polycystic Kidney Disease	Cats	1mls EDTA blood ****	£34	pdf
Equine
Chestnut Gene In Horses	Horses	3-5mls EDTA blood ****	£70	pdf
Overo Coat Colour	Horses	Plucked Mane or Tail Hairs	£70	pdf
£115 incl VAT when both tests requested together for Staffordshire Bull Terrier * £82 incl VAT when both tests requested together for English Springer Spaniels * For Springerklubben (Sweden) Only ** EDTA blood samples only accepted for dogs from countries within the E U Discounts for 20 or more samples submitted together as one consignment and covered by one payment for total amount payable, please contact us for details dnatesting@aht.org.uk

With immediate effect (15 October 2009) we are no longer able to accept blood samples from outside the European Union

Feline

Breed	Test	Sample Required	Price (inc vat)	Request Form
Cats	Polycystic Kidney Disease	1mls EDTA blood ****	£34	pdf

Equine

Breed	Test	Sample Required	Price (inc vat)	Request Form
Horses	Chestnut Gene In Horses	3-5mls EDTA blood ****	£70	pdf
Horses	Overo Coat Colour	Plucked Mane or Tail Hairs	£70	pdf
Fell, Dales and Part-Breds	Foal Immunodeficiency Syndrome (FIS)	Plucked Mane or Tail Hairs	For information about sample submission and invoicing please click here FAQ

Cattle

Breed	Test	Sample Required	Cost per animal
Cattle	Parentage/Profiling	Plucked Hairs	£20 plus VAT

Samples for DNA profiling or parentage analysis in cattle can be semen or hairs. Hairs must be plucked not cut, and should be submitted in a labelled bag obtainable free of charge by contacting Symone Ingram on tel 01638 555621 or e-mail dnatesting@aht.org.uk.

The Animal Health Trust has robust procedures in place for tracking samples at all stages of processing, ensuring the reliability of our DNA testing service. However, as samples are identified and processed using information supplied by the owner on the accompanying Request for DNA Testing form, owners must make certain that the details given on that form are accurate and that each form is clearly associated with the correct sample(s).

Prices applicable from 1st January 2010. Fees are payable upon submission. Credit card payments can be made by providing the following information:

Card number - Name on card - Expiry date - Valid from date- Security number - Issue number

Results will be issued as soon as they are ready- not by telephone but by e-mail and post only as completed on the test request form.