Below we have outlined the products available in the UK and have included the recommended dosing schedules.

UK vaccines

Equip F

Virus strains include:
• European H3N8 – Borlänge/91
• American H3N8 – Kentucky/98
• H7N7 – Newmarket/77

Recommended dosing regime: primary course – 1st vaccine from the age of 4 months, 2nd vaccination 6 weeks after the first, 3rd vaccination 5 months after the second. Boosters every 12-15 months thereafter.

Zoetis producers of Equip F. Telephone: 0845 3008034. Email: ukvetline@zoetis.com

Equilis Prequenza

Virus strains include:

• European H3N8 – Newmarket/2/93

• Florida Clade 1 H3N8 – South Africa/4/03

Recommended dosing regime: primary course – 1st vaccination from the age of 6 months, 2nd vaccination 4 weeks after the first, 3rd vaccination 5 months after the second. Boosters every 12 months thereafter.

MSD Animal Health producers of Equilis Prequenza. Telephone: 01908 685685. Email: vets-support.uk@merk.com

ProteqFlu, ProteqFlu-TE

Equine influenzavirus strains included:

• Florida Clade I H3N8 – Ohio/03

• Florida Clade 2 H3N8 – Richmond/1/07

Recommended dosing regime: primary course – 1st injection from the age of 5-6 months, 2nd injection 4-6 weeks after the first, 3rd injection 5 months after the primary course. Boosters every 12 months thereafter.

Boehringer Ingelheim Animal Health UK Ltd producers of ProteqFlu. Telephone: 01344 746957. Email: vetenquiries@boehringer-ingelheim.com

Vaccine strains

Like other influenza viruses, equine influenza constantly changes so vaccine strains need to be updated periodically.

Information is collected from viruses from all over the world, which is used to recommend suitable strains for vaccines. As part of this process the AHT carries out surveillance in the UK, sponsored by the HBLB. An independent panel of experts, including AHT scientists, meet every year to select strains.

The official recommendations, approved by the World Organisation for Animal Health (OIE), are available on the OIE website. These are also published annually in their second quarterly bulletin which you can download below.

Current recommendations

Vaccines for the international market should contain both clade 1 and clade 2 viruses of the Florida sublineage:

Clade 1 is represented by A/eq/South Africa/04/2003-like or A/eq/Ohio/2003-like viruses.

Clade 2 is represented by A/eq/Richmond/1/2007-like viruses

The recommendations have not been changed since 2010. Two vaccines available in the UK contain a recommended Clade 1 strain, only one product contains a recommended Clade 2 strain.

UK vaccines and OIE recommendations

Vaccine name Conform to 1995 recommendations Conform to 2004 recommendations Conform to 2010 recommendations
Equip F
Equilis Prequenza
ProteqFlu

Vaccination regulations and dosing regimes

To ensure that horses gain the maximum protection from vaccination, vaccines need to be given according to the manufacturer’s instructions on the product label.

The FEI and BHA regulations allow vaccination within a wide range of dates, but to ensure the optimum performance from any one type of vaccine the product label must be followed accurately.

To provide optimum protection please use the same product for all three doses of the primary course.

FEI regulations

• A primary course of two vaccinations between 21 and 92 days apart (3 weeks to 3 months).

• A third vaccination within 7 months of the second vaccination.

• Thereafter boosters must be within a year.

• All horses being entered for FEI competition must have received an equine influenza booster vaccination a maximum of 6 months +21 days before the day of competition entry.

• Horses may not be vaccinated within 7 days of arrival at the FEI event.

In reality all horses competing regularly will need to have biannual boosters.

All equine influenza vaccines currently available in the UK are permitted by the FEI.

BHA regulations

• A primary course of two vaccinations between 21 and 92 days apart (3 weeks to 3 months).

• A third vaccination between 150 and 215 days after the second vaccination.

• Further booster vaccinations at intervals of not more than a year apart.

None of the vaccinations must have been given on the day of a race in which the horse is declared to run or on any of the 6 days before the race.

All equine influenza vaccines currently available in the UK are permitted by the BHA.

Adverse events and reporting

Any adverse events that a horse experiences after receiving an influenza vaccination should be reported to the vaccine manufacturer, even if the vaccine has been used off label. This is one of the major ways the manufacturers monitor both the safety and efficacy of their products.

The Veterinary Medicines Directorate (VMD) also monitors the safety and efficacy of veterinary products in the UK.

Adverse events include:

1. Suspected failure to protect – i.e. a horse that develops signs of influenza when a product is used according to the label.

2. Any reactions, clinical signs or illness that follows injection either on or off label

Adverse reactions can be reported directly to the vaccine manufacturers or to the VMD by filling out the form below. If a horse has received more than one type of vaccine then it is the manufacturer of the last vaccine given that should be reported to.

Contact details for reporting adverse reactions:

Adverse events should be reported to the VMD, either online on the VMD website or by post using the adverse event reporting form which can be downloaded below.

Adverse Event Reporting forms can also be requested from:

Veterinary Medicines Directorate
FREEPOST KT4503
Woodham Lane
New Haw
Addlestone
Surrey KT15 3BR.

Influenza in vaccinated horses

We would particularly like to hear from you if you have a case of influenza in a horse that has been vaccinated on-label.

Contact: 01638 751000

Email: equiflunet@aht.org.uk

Supported by Horserace Betting Levy Board