Serology

Providing serology diagnostics to veterinary surgeons and research institutes, we use a combination of modern and classic techniques to identify exposure to a range of veterinary pathogens.

Our tests

  • ELISA – Many of our tests make use of the Enzyme Linked Immunosorbant Assay. We take great pride in translating the world-class research at the AHT into robust, high quality diagnostic tests to help inform clinical management and to have a tangible effect on animal welfare
  • CF – We employ the Complement Fixation test to provide serological testing for Equine Herpesvirus and Equine Rhinitis
  • HI – We employ Haemagglutination Inhibition assays to screen for Equine Influenza and Adenovirus antibodies
  • VN – Through preserving classical methodologies and having the ability to do mammalian tissue culture, we are able to offer Virus Neutralisation assays for Equine Herpesvirus 3 and Equine Viral Arteritis.

But your samples journey doesn’t need to end there; within our state-of-the-art laboratory complex the serology labs sit surrounded by our world leading research groups.

Working with epidemiologists we can help you control and clear outbreaks of infectious diseases. If we isolate the pathogen we can also pass the strain to our researchers who characterise it. This lets us make decisions/recommendations across several areas:

  • Pathogenicity and mechanisms of disease
  • Disease epidemiology and virus evolution
  • Test & Vaccine Quality Assurance; Are the vaccines and tests fit for purpose?

We regularly review the technology and science behind out tests to ensure they remain fit for purpose; it is also part of our ISO17025 Accreditation.

It is important to us that we make the right tests available to our clients, to give you confidence in using our results to inform your practice.

This synergy between diagnostics and research has lead us to become the OIE Reference Laboratories for Equine Herpesvirus and Equine Influenza.

The AHT Diagnostic service also offer a comprehensive range of pre-breeding testing to cover your clients every need.

Equine Infectious Anaemia (EIA) testing for horses imported from countries outside of EU member states

Correspondence from the Directorate General for Health and Food Safety, European Commission, summarised the animal health and veterinary certification conditions for the entry into the Union of equidae from countries outside EU member states. These conditions were adopted on 12 April 2018 and apply as of 1 October 2018.

These entry conditions now foresee equivalence between Agar Gel Immunodiffusion (AGID) Coggins test and the ELISA for EIA testing and this has been recommended by the World Organization for Animal Health (OIE).

The laboratory in the United States which performs the tests for export certification has migrated the testing for EIA from AGID to ELISA.

In a recent consignment of horses arriving from the USA, this was correctly recorded in the accompanying certificate by amending the relevant attestation set out in Annex II (C) to Decision 93/197/EEC.

In order to avoid trade problems, please be aware of this revision. Consignments in which the test for EIA is indicated as ‘ELISA’ and the ‘Coggins test’ is deleted are valid conditions for entry.

Equip Artervac (Zoetis) post-vaccination serological monitoring 2017-2018

Veterinary vaccine manufacturer Zoetis has warned of supply problems with its equine viral arteritis (EVA) vaccine, Equip Artervac, which will lead to an as yet undetermined interval in supply after their currently available batch expires on 26thNovember 2017.  This will result in vaccinated stallions and teasers effectively ‘lapsing’ at six months after their last vaccination if Artervac is not available for the next recommended six-monthly booster dose.  In August 2017, the Thoroughbred Breeders’ Association advised their members to booster vaccinate or complete a primary vaccine course before 26th November 2017, any stallions/teasers that will be covering/teasing in 2018.

AHT Equine Infectious Disease Service

The Animal Health Trust (AHT) is extremely grateful to the Horserace Betting Levy Board (HBLB), Racehorse Owners Association (ROA) and Thoroughbred Breeders’ Association (TBA) for their continued combined contribution to the AHT’s Equine Infectious Disease Service, which in particular supports key staff within the Diagnostic Laboratory and Pathology Service and allows enhanced investigation and control of significant equine infectious diseases in the United Kingdom.